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C0688000

Cefoxitin sodium

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Cefoxitin sodium salt

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About This Item

Empirical Formula (Hill Notation):
C16H16N3NaO7S2
CAS Number:
33564-30-6
Molecular Weight:
449.43
MDL number:
MFCD00079042
UNSPSC Code:
41116107
PubChem Substance ID:
329774813
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

cefoxitin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[Na+].CO[C@]2(NC(=O)Cc1cccs1)C3SCC(COC(N)=O)=C(N3C2=O)C([O-])=O

InChI

1S/C16H17N3O7S2.Na/c1-25-16(18-10(20)5-9-3-2-4-27-9)13(23)19-11(12(21)22)8(6-26-15(17)24)7-28-14(16)19;/h2-4,14H,5-7H2,1H3,(H2,17,24)(H,18,20)(H,21,22);/q;+1/p-1/t14-,16+;/m1./s1

InChI key

GNWUOVJNSFPWDD-XMZRARIVSA-M

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cefoxitin sodium EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Precautionary Statements

P280 - P302 + P352

Hazard Classifications

Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

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Mohammed Shahid et al.
Journal of clinical microbiology, 50(5), 1779-1782 (2012-02-18)
Cefoxitin-resistant Escherichia coli (n = 109) and Klebsiella pneumoniae (n = 16) isolates collected from patients in India in 2009 to 2010 were screened for bla(ampC) families and mobilizing elements (ISEcp1, IS26, ISCR1, and sul-1-type class 1 integrons) and their
Arantxazu Isla et al.
European journal of clinical pharmacology, 68(5), 735-745 (2012-01-17)
To elucidate whether a dose of 2 g cefoxitin as a prophylactic agent in patients undergoing elective colorectal surgery is able to maintain free drug concentrations above the minimum inhibitory concentration of the microorganisms involved in surgical site infection. This
Yang Tsuey-Ching et al.
Research in microbiology, 163(8), 550-556 (2012-08-23)
In Xanthomonas campestris pv. campestris (Xcc), the chromosomally encoded class A β-lactamase (Bla(xcc)) is expressed at a high basal level in the absence of an inducer and its expression is inducible by ampicillin. Like most of the class A β-lactamases
Matthew P Kronman et al.
Pediatrics, 130(4), e794-e803 (2012-09-26)
To determine whether childhood antianaerobic antibiotic exposure is associated with the development of inflammatory bowel disease (IBD). This retrospective cohort study employed data from 464 UK ambulatory practices participating in The Health Improvement Network. All children with ≥ 2 years
Marion J Skalweit et al.
Antimicrobial agents and chemotherapy, 57(4), 1596-1602 (2013-01-16)
Class C cephalosporinases are a growing threat, and clinical inhibitors of these enzymes are currently unavailable. Previous studies have explored the role of Asn152 in the Escherichia coli AmpC and P99 enzymes and have suggested that interactions between C-6' or
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