1.00577

Water

suitable for GC-HS, SupraSolv^®, according to USP and Ph. Eur.

• Linear Formula: H₂O
• CAS Number: 7732-18-5
• Molecular Weight: 18.02
• Beilstein: 2050024
• MDL number: MFCD00011332
• UNSPSC Code: 41104213
• NACRES: NA.03

Properties

• product name: Water, for headspace gas chromatography SupraSolv^®
• Agency: according to Ph. Eur.; according to USP
• Quality Level: 100
• vapor pressure: 23 hPa ( 20 °C)
• product line: SupraSolv^®
• form: liquid
• technique(s): GC-HS: suitable
• impurities: ≤1 μg/g Every residual solvent of class 1 acc. to ICH; ≤10 μg/g Every residual solvent of class 2 acc. to ICH; ≤50 μg/g Every residual solvent of class 3 acc. to ICH
• evapn. residue: ≤5 mg/L
• refractive index: n20/D 1.34 (lit.)
• pH: 7 (20 °C)
• bp: 100 °C (lit.)
• mp: 0 °C (lit.)
• density: 1.000 g/mL at 3.98 °C (lit.)
• storage temp.: 2-30°C
• SMILES string: O
• InChI: 1S/H2O/h1H2
• InChI key: XLYOFNOQVPJJNP-UHFFFAOYSA-N

Description

General description

SupraSolv solvents for headspace gas chromatography are developed particularly for the analysis of residual solvents in drug substances, excipients and drug products according to ICH, Ph Eur and USP - SupraSolv headspace solvents are tested for all residual solvents defined by the ICH.

Application

• Novel Insights into Sb(III) Oxidation and Immobilization during Ferrous Iron Oxygenation: The Overlooked Roles of Singlet Oxygen and Fe (oxyhydr)oxides Formation.: Discusses the impact of water chemistry on the oxidation processes of antimony and iron, contributing to environmental chemistry and pollution control (Wang et al., 2024).


• Exposure And Health Risk Assessment Of Aflatoxins In Hot Red Pepper Marketed In North Shewa Zone, Oromia Region, Ethiopia.: Assesses the role of water in transporting and dissolving aflatoxins, with implications for food safety and analytical methodologies in developing countries (Alemu Degefe et al., 2024).

Analysis Note

residue on evaporation: ≤ 5 mg/l
GC/HS
Every residual solvent of class 1 acc. to ICH: ≤ 1 µg/g
Every residual solvent of class 2 acc. to ICH: ≤ 10 µg/g
Every residual solvent of class 3 acc. to ICH: ≤ 50 µg/g
Suitable as solvent for the analysis of residual solvents of ICH classes 1, 2 and 3 according to Ph Eur and USP.
Formic acid, acetic acid, N,N-dimethylacetamide, N,N-dimethy lformamide and dimethyl sulfoxide are not detected.

Other Notes

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Legal Information

SUPRASOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point(F): No data available
• Flash Point(C): No data available