I9148

Sodium iodoacetate

powder, ≥98%

• Synonym(s): Iodoacetic acid sodium salt
• Linear Formula: ICH₂COONa
• CAS Number: 305-53-3
• Molecular Weight: 207.93
• Beilstein: 4009322
• EC Number: 206-165-7
• MDL number: MFCD00002686
• UNSPSC Code: 12352202
• PubChem Substance ID: 24896151
• NACRES: NA.77

Properties

• product name: Sodium iodoacetate, ≥98%, BioUltra
• biological source: synthetic (organic)
• product line: BioUltra
• Assay: ≥98%
• form: powder
• impurities: ≤0.0005% Phosphorus (P); ≤0.1% Insoluble matter
• mp: 208 °C (dec.) (lit.)
• solubility: H₂O: 0.5 M, clear, colorless
• anion traces: sulfate (SO₄^2-): ≤0.05%
• cation traces: Al: ≤0.0005%; Ca: ≤0.001%; Cu: ≤0.001%; Fe: ≤0.0005%; K: ≤0.02%; Mg: ≤0.0005%; NH₄⁺: ≤0.05%; Pb: ≤0.001%; Zn: ≤0.0005%
• storage temp.: −20°C
• SMILES string: [Na+].[O-]C(=O)CI
• InChI: 1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1
• InChI key: AGDSCTQQXMDDCV-UHFFFAOYSA-M

Description

Application

Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.

Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

Safety Information

• Pictograms: GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H301,H314
• Precautionary Statements: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 406.4 °F
• Flash Point(C): 208 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves