S-002

Secobarbital solution

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₂H₁₈N₂O₃
• CAS Number: 76-73-3
• Molecular Weight: 238.28
• MDL number: MFCD00056088
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)
• concentration: 1 mg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: 2-8°C
• SMILES string: CCCC(C)C1(CC=C)C(=O)NC(=O)NC1=O
• InChI: 1S/C12H18N2O3/c1-4-6-8(3)12(7-5-2)9(15)13-11(17)14-10(12)16/h5,8H,2,4,6-7H2,1,3H3,(H2,13,14,15,16,17)
• InChI key: KQPKPCNLIDLUMF-UHFFFAOYSA-N
• Gene Information: human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

Description

General description

Secobarbital, sold under the trade name Seconal^®, is a barbiturate approved for treatment of epilepsy as well as temporary treatment of insomnia. The drug is also used as a preoperative anesthetic in short surgical, diagnostic or therapeutic procedures. This Certified Spiking Solution^® is suitable for numerous GC/MS or LC/MS testing applications from clinical toxicology to urine drug testing and forensic analysis.

Application

• Barbiturate assay standardization: A research article presents a comprehensive protocol for high-throughput quantitative LC-MS/MS analysis of barbiturates, including Secobarbital, in human urine. This study is pivotal for clinical toxicology and forensic analysis, supporting accurate and efficient barbiturate detection (Gqamana and Zhang, 2024).



• Development of analytical techniques for Secobarbital: Another study details the specific analysis of Secobarbital in urine using LC-MS/MS. This research enhances the understanding of barbiturate metabolism and excretion, critical for both clinical and research settings (Campbell et al., 2024).

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Seconal is a registered trademark of Marathon Pharmaceuticals, LLC

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup