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  • A dual modal silver bumpy nanoprobe for photoacoustic imaging and SERS multiplexed identification of in vivo lymph nodes.

A dual modal silver bumpy nanoprobe for photoacoustic imaging and SERS multiplexed identification of in vivo lymph nodes.

Nanoscale (2017-08-19)
Myeong Geun Cha, Seunghyun Lee, Sungjo Park, Homan Kang, Sung Gun Lee, Cheolhwan Jeong, Yoon-Sik Lee, Chulhong Kim, Dae Hong Jeong
ABSTRACT

Multimodal imaging can provide complementary biomedical information which has huge potential in pre-clinical and clinical imaging and sensing. In this study, we introduce dual modal NIR silver bumpy nanoprobes for in vivo imaging and multiplexed detection of biomolecules by both photoacoustic imaging (PAI) and surface-enhanced Raman scattering (SERS) techniques. For this study, we used silica-coated silver bumpy nanoshell probes (AgNS@SiO

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
4-Chlorothiophenol, 97%
Sigma-Aldrich
4-Bromothiophenol, 95%
Sigma-Aldrich
4-Fluorothiophenol, 98%
Sigma-Aldrich
(3-Mercaptopropyl)trimethoxysilane, 95%