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Key Documents

A8131

Sigma-Aldrich

D-Asparagine monohydrate

≥99% (TLC)

Synonym(s):

(R)-(-)-2-Aminosuccinamic acid, (R)-2-Aminosuccinic acid 4-amide, (D)-Aspartic acid 4-amide

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About This Item

Linear Formula:
NH2COCH2CH(NH2)COOH · H2O
CAS Number:
Molecular Weight:
150.13
Beilstein:
1723526
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26

product name

D-Asparagine monohydrate, ≥99% (TLC)

Assay

≥99% (TLC)

form

powder or crystals

color

white to off-white

mp

275 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

NC(C[C@@H](N)C(O)=O)=O.[H]O[H]

InChI

1S/C4H8N2O3.H2O/c5-2(4(8)9)1-3(6)7;/h2H,1,5H2,(H2,6,7)(H,8,9);1H2/t2-;/m1./s1

InChI key

RBMGJIZCEWRQES-HSHFZTNMSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Daniel L Kirschner et al.
Journal of separation science, 32(13), 2305-2318 (2009-07-02)
The increase in our understanding of D-amino acid function and distribution in mammals is in many ways a result of the initial development of sensitive enantioselective separation strategies that allow for quantification in real biological samples. This article reviews progress
Wouter F Visser et al.
Journal of chromatography. A, 1218(40), 7130-7136 (2011-09-06)
D-Amino acids are increasingly being recognized as important signaling molecules in mammals, including humans. D-Serine and D-aspartate are believed to act as signaling molecules in the central nervous system. Interestingly, several other D-amino acids also occur in human plasma, but
Ju Li et al.
Analytical chemistry, 74(14), 3336-3341 (2002-07-26)
Asparaginase from the hyperthermophilic microorganism Archaeoglobus fulgidus was cloned and expressed in Escherichia coli as a fusion protein with a polyhistidine tail. After heat treatment to denature most of the native E. coli proteins, the enzyme was purified by an
Yaru Song et al.
Analytical chemistry, 78(23), 8121-8128 (2006-12-01)
A sensitive chiral capillary HPLC-MS/MS method well suited for the determination of amino acid enantiomers in biological samples was developed. The method involved precolumn derivatization of the sample with 7-fluoro-4-nitrobenzoxadiazole (NBD-F). After derivatization, NBD-amino acids were stacked on a C18

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