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71238

Sigma-Aldrich

Alginic acid sodium salt from brown algae

BioReagent, suitable for immobilization of micro-organisms

Synonym(s):

Algin, Sodium alginate

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About This Item

CAS Number:
9005-38-3
MDL number:
MFCD00081310
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

algae (brown)

product line

BioReagent

form

powder

ign. residue

≤30%

loss

≤15% loss on drying

color

white to light beige

pH

6.0-8.0 (10 mg/mL in H2O)

suitability

in accordance for gelation test
suitable for immobilization of micro-organisms

storage temp.

room temp

InChI

1S/C6H10O7.Na/c7-1-2(8)4(5(10)11)13-6(12)3(1)9;/h1-4,6-9,12H,(H,10,11);/q;+1/p-1/t1-,2-,3-,4?,6+;/m0./s1

InChI key

MSXHSNHNTORCAW-MPGIDXPLSA-M

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Application

Alginate, a colloidal polyuronic acid structural molecule capable of gelation, is used in the preparation of colloidal biodegradable structures such as gels, biofilms, beads, nanoparticles, and microcapsules suitable for applications that range from gel based separation technologies to drug delivery and cell preservation.

Other Notes

A straight-chain, hydrophilic, colloidal, polyuronic acid composed of guluronic and mannuronic acid residues.
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Immobilization of cells; or enzymes; the alginate matrix can be liquefied by the addition of a chelating agent, making possible the recovery of developing colonies without affecting their continued growth.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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O Smidsrød et al.
Trends in biotechnology, 8(3), 71-78 (1990-03-01)
In recent years, entrapment of cells within spheres of Ca2+ alginate has become the most widely used technique for immobilizing living cells. This versatile method includes applications ranging from immobilization of living or dead cells in bioreactors, immobilization of plant
W.H. Scouten
Solid Phase Biochemistry, 449-449 (1983)
C. Bucke
Methods in Enzymology, 135, 175-175 (1987)
Andreas Blaeser et al.
Advanced healthcare materials, 5(3), 326-333 (2015-12-03)
A microvalve-based bioprinting system for the manufacturing of high-resolution, multimaterial 3D-structures is reported. Applying a straightforward fluid-dynamics model, the shear stress at the nozzle site can precisely be controlled. Using this system, a broad study on how cell viability and
Mikhail Y Maslov et al.
Journal of controlled release : official journal of the Controlled Release Society, 194, 257-265 (2014-09-23)
Prior studies in small mammals have shown that local epicardial application of inotropic compounds drives myocardial contractility without systemic side effects. Myocardial capillary blood flow, however, may be more significant in larger species than in small animals. We hypothesized that
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