937606
Dipyridyl dithiocarbonate
≥95%
Synonym(s):
DPDTC, Di-2-pyridyl dithiocarbonate
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About This Item
Empirical Formula (Hill Notation):
C11H8N2OS2
CAS Number:
Molecular Weight:
248.32
MDL number:
UNSPSC Code:
12352142
NACRES:
NA.21
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Quality Level
Assay
≥95%
form
powder or crystals
color
off-white to yellow, to Beige
storage temp.
2-8°C
SMILES string
O=C(SC1=NC=CC=C1)SC2=NC=CC=C2
InChI
InChI=1S/C11H8N2OS2/c14-11(15-9-5-1-3-7-12-9)16-10-6-2-4-8-13-10/h1-8H
InChI key
BMMLAAKESBFUOH-UHFFFAOYSA-N
General description
Dipyridyl dithiocarbonate, or DPDTC, as reported by the Lipshutz lab, is an effective peptide coupling reagent that is active across a broad substrate scope under mild conditions. Additionally, as DPDTC is functionally similar to thioesters utilized in biological peptide formation, it can be utilized in aqueous media, and avoids many of the hazardous side products and safety concerns present in many other current peptide coupling strategies.
Features and Benefits
Functional in water
Broad substrate scope
Usable under mild conditions
Avoids hazardous coupling reagents
Broad substrate scope
Usable under mild conditions
Avoids hazardous coupling reagents
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Direct formation of amide/peptide bonds from carboxylic acids: no traditional coupling reagents, 1-pot, and green
Freiberg M K, et al.
Chemical Science, 14(13), 3462-3469 (2023)
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