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LC/MS Analysis of Illicit Bath Salts on Ascentis® Express HILIC, Set 3

LC/MS Analysis of Illicit Bath Salts on Ascentis® Express HILIC, Set 3 application for HPLC

Materials

analytical column

Product No.
Description
Pricing

Ascentis® Express HILIC, 2.7 μm HPLC Column

2.7 μm particle size, L × I.D. 10 cm × 2.1 mm

Application

Product No.
Description
Pricing

LC/MS Analysis of Illicit Bath Salts on Ascentis® Express HILIC, Set 1

application for HPLC

LC/MS Analysis of Illicit Bath Salts on Ascentis® Express HILIC, Set 2

application for HPLC

LC/MS Analysis of Illicit Bath Salts on Ascentis® Express HILIC, Set 4

application for HPLC

standard

Product No.
Description
Pricing

4-Fluoromethcathinone hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

3-Fluoromethcathinone hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

4-Methylethcathinone hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Pentedrone hydrochloride

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

CONDITIONS

column

Ascentis Express HILIC, 10 cm x 2.1 mm I.D., 2.7 μm particles (53939-U)

mobile phase

[A] 5 mM ammonium formate in acetonitrile; [B] water; (98:2, A:B)

flow rate

0.6 mL/min

pressure

267 psi (18.4 bar)

column temp.

35 °C

detector

MS, ESI(+) TOF, Summed Ion Chromatogram

injection

2 μL

sample

500 ng/mL in acetonitrile

Description

Analysis Note

HILIC mode operation on an Ascentis Express column provided baseline resolution of these bath salts, including isobaric compounds. The highest quality LC-MS solvents were used to supply low background interference and low particulate contaminants for robust; trouble-free operation. Cerilliant CRMs provided reliable identification and quantification.

Legal Information

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany