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Merck

Alleviation by GABA

Neurochemical research (2017-06-14)
Toshihiko Kinjo, Yoshino Ashida, Hiroshi Higashi, Satoshi Sugimura, Miho Washida, Hiroki Niihara, Kiyokazu Ogita, Yukio Yoneda, Nobuyuki Kuramoto
ABSTRACT

Mitochondrial permeability transition pore (PTP) is supposed to at least in part participate in molecular mechanisms underlying the neurotoxicity seen after overactivation of N-methyl-D-aspartate (NMDA) receptor (NMDAR) in neurons. In this study, we have evaluated whether activation of GABA

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
3,3′-Dipropylthiacarbocyanine iodide, 98%
Sigma-Aldrich
R(+)-Baclofen hydrochloride, solid
Sigma-Aldrich
N-Methyl-D-aspartic acid, ≥98% (TLC), solid