- Leishmania infantum lipophosphoglycan induced-Prostaglandin E
Leishmania infantum lipophosphoglycan induced-Prostaglandin E
Scientific reports (2017-11-01)
Jonilson Berlink Lima, Théo Araújo-Santos, Milena Lázaro-Souza, Alan Brito Carneiro, Izabela Coimbra Ibraim, Flávio Henrique Jesus-Santos, Nívea Farias Luz, Sara de Moura Pontes, Petter Franco Entringer, Albert Descoteaux, Patrícia Torres Bozza, Rodrigo Pedro Soares, Valéria Matos Borges
PMID29084985
ABSTRACT
Lipophosphoglycan (LPG) is a key virulence factor expressed on the surfaces of Leishmania promastigotes. Although LPG is known to activate macrophages, the underlying mechanisms resulting in the production of prostaglandin E