[Current views on diagnostic standards and treatments with L-thyroxine of single non-toxic thyroid nodules or multinodular non-toxic goiter].

The present opinions on the therapy with L-thyroxine (L-T4) of single non-toxic thyroid nodules, as well as of multinodular non-toxic goitre are rather divergent. This treatment is based on the suppression of TSH secretion from the pituitary. There are no doubts that FNAB performance is the first and--at the same time--the most significant diagnostic procedure in the case of thyroid structural lesions (nodules, goitre, thyroiditis). FNAB performance should--by all means--precede the beginning of L-T4 application for the treatment of thyroid nodules. The simplicity, clearness and high efficacy, with comparable results in each case, are the core of good diagnostic algorithm. Unfortunately, non all diagnostic algorithms concerning thyroid nodules and multinodular goiter, fulfill these important criteria.