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Merck

Metal ion levels: how can they help us?

The Journal of arthroplasty (2014-03-25)
William L Griffin
ABSTRACT

Ion levels have been shown to reliably predict abnormal function of the bearing surface with increased wear, but ion levels should not be used alone as a trigger for when to proceed with revision surgery with metal-metal articulations. Risk stratification strategies help determine which patients should be monitored more closely with serial ion levels, cross-sectional imaging with a MARS MRI, or proceed on to revision. Based on the current data available, an ion level greater than 4.5 ppb (Cr or Co) may serve as a threshold for when abnormal wear is occurring, and is suggested as a trigger for a MARS MRI scan.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Cobalt, Carbon coated magnetic, nanopowder, <50 nm particle size (TEM), ≥99%
Sigma-Aldrich
Cobalt, powder, 2 μm particle size, 99.8% trace metals basis
Sigma-Aldrich
Cobalt, powder, <150 μm, ≥99.9% trace metals basis
Sigma-Aldrich
Cobalt, foil, thickness 1.0 mm, 99.95% trace metals basis
Sigma-Aldrich
Cobalt, foil, thickness 0.1 mm, 99.95% trace metals basis
Sigma-Aldrich
Cobalt, rod, diam. 5.0 mm, 99.95% trace metals basis
Sigma-Aldrich
Cobalt, pieces, 99.5% trace metals basis
Sigma-Aldrich
Cobalt, wire, diam. 1.0 mm, 99.995% trace metals basis
Sigma-Aldrich
Chromium, chips, 99.995% trace metals basis
Sigma-Aldrich
Chromium, chips, thickness ~2 mm, 99.5%
Sigma-Aldrich
Cobalt, granular, 99.99% trace metals basis
Sigma-Aldrich
Chromium, powder, ≥99% trace metals basis, <45 μm
Cobalt, foil, 8mm disks, thickness 0.009mm, 99.9%
Cobalt, foil, not light tested, 50x50mm, thickness 0.002mm, temporary acrylic support, 99.9%
Cobalt, foil, 8mm disks, thickness 0.01mm, 99.9%
Cobalt, foil, light tested, 25x25mm, thickness 0.009mm, 99.9%
Cobalt, foil, 6mm disks, thickness 0.125mm, as rolled, 99.99+%
Cobalt, foil, 8mm disks, thickness 0.005mm, 99.9%
Cobalt, foil, 8mm disks, thickness 0.0125mm, 99.9%
Cobalt, foil, 6mm disks, thickness 0.25mm, as rolled, 99.9%
Cobalt, foil, not light tested, 25x25mm, thickness 0.005mm, 99.9%
Cobalt, foil, 8mm disks, thickness 0.015mm, 99.9%
Cobalt, foil, 8mm disks, thickness 0.125mm, annealed, 99.9%
Cobalt, microfoil, disks, 10mm, thinness 0.5μm, specific density 434μg/cm2, permanent mylar 3.5μm support, 99.9%
Cobalt, foil, not light tested, 50x50mm, thickness 0.007mm, 99.9%
Cobalt, foil, not light tested, 150x150mm, thickness 0.0125mm, 99.9%
Cobalt, wire reel, 0.1m, diameter 1.0mm, hard, 99.99+%
Cobalt, foil, 8mm disks, thickness 0.003mm, 99.9%
Cobalt, foil, 8mm disks, thickness 0.25mm, as rolled, 99.99+%
Cobalt, foil, light tested, 50x50mm, thickness 0.01mm, 99.9%