Skip to Content
Merck
All Photos(1)

Documents

E0528

Sigma-Aldrich

Ephrin-A5/Fc Chimera human

>90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Synonym(s):

AL-1, EFL-5, LERK-7, RAGS

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

MDL number:
MFCD01867034
UNSPSC Code:
51111800
NACRES:
NA.32

biological source

human

Quality Level

200

recombinant

expressed in NSO cells

Assay

>90% (SDS-PAGE)

form

lyophilized powder

mol wt

monomer calculated mol wt 48.6 kDa
 50-55 kDa by SDS-PAGE (reducing)

packaging

pkg of 200 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

UniProt accession no.

P52803

storage temp.

−20°C

Gene Information

human ... EFNA5(1946)

General description

Extracellular domain of human ephrin-A4 (amino acids 1-203) was fused to the C-terminal 6X histidine-tagged Fc region of human IgG1.

Biochem/physiol Actions

Member of the ephrin ligand family that binds Eph receptor tyrosine kinases (EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, and Eph8). Involved in pattern formation and morphogenesis.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Analysis Note

The biological activity is measured by its ability to compete with biotinylated human Ephrin-A5/Fc chimera for binding with recombinant mouse EphA3/Fc in ELISA.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Takahiro Sawada et al.
PloS one, 12(7), e0180785-e0180785 (2017-07-08)
We previously reported that EphA4, a member of the Eph family of receptor tyrosine kinases, is an important modulator of growth hormone (GH) signaling, leading to augmented synthesis of insulin-like growth factor 1 (IGF1) for postnatal body growth. In the

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service