C7628
5β-Cholanic acid
≥99% (TLC)
Synonym(s):
Ursocholanic acid
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About This Item
Empirical Formula (Hill Notation):
C24H40O2
CAS Number:
Molecular Weight:
360.57
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.77
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Quality Level
Assay
≥99% (TLC)
form
powder
SMILES string
[H]C12CCCCC1(C)C3CCC4(C)C(CCC4C3CC2)[C@@H](C)CCC(O)=O
InChI
1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)
InChI key
RPKLZQLYODPWTM-UHFFFAOYSA-N
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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L Campanella et al.
Journal of pharmaceutical and biomedical analysis, 11(11-12), 1207-1214 (1993-11-01)
An ISFET device selective for cholanic acids, based on a PVC-sebacate membrane, containing benzyldimethylcetylammoniumcholate as exchanger, has been prepared, characterized and applied to the determination of cheno or ursodeoxycholic acid content of commercial pharmaceutical drugs and critical micellar concentration (CMC)
Y Mori et al.
Mutation research, 262(4), 267-274 (1991-04-01)
Published data on the mutagenicity of 3 bile acids in the bacterial fluctuation test are conflicting. Eleven 5 beta-cholanoic acids including 2 of the bile acids were assayed for mutagenicity in Salmonella typhimurium TA98 and TA100 in the fluctuation tests.
Guohao Wang et al.
ChemMedChem, 13(1), 78-86 (2017-11-01)
The delivery of therapeutic cancer agents using nanomaterials has recently attracted much attention. Although encouraging progress with chemotherapeutics has been made, tumor treatment response remains unsatisfactory. To address this concern, we constructed a new micellar nanocomplex by covalently conjugating hyaluronic
Kyeongsoon Park et al.
Journal of controlled release : official journal of the Controlled Release Society, 122(3), 305-314 (2007-07-24)
To improve the in vivo tumor targeting characteristics of polymeric nanoparticles, three glycol chitosan (GC-20 kDa, GC-100 kDa, and GC-250 kDa) derivatives with different molecular weights were modified with cholanic acid at the same molar ratio. The resulting amphiphilic glycol
Jin Hee Na et al.
Journal of controlled release : official journal of the Controlled Release Society, 163(1), 2-9 (2012-08-01)
To evaluate the tumor targeting efficiency of self-assembled polymeric nanoparticles, four glycol chitosan nanoparticles (CNPs) with different degrees of hydrophobic substitution were prepared by coupling 7.5, 12, 23, and 35 wt.% of 5β-cholanic acid to hydrophilic glycol chitosan polymer (GC).
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