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C5108

Sigma-Aldrich

Cathepsin G from human sputum

≥0.2 units/mg protein, salt-free, lyophilized powder

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About This Item

CAS Number:
Enzyme Commission number:
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human sputum

form

salt-free, lyophilized powder

specific activity

≥0.2 units/mg protein

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... CTSG(1511)

Biochem/physiol Actions

Cathepsin G has pro-apoptotic activity and can activate caspases in vitro.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Dawid Dębowski et al.
Peptides, 35(2), 276-284 (2012-04-21)
A series of linear and cyclic fragments and analogs of two peptides (OGTI and HV-BBI) isolated from skin secretions of frogs were synthesized by the solid-phase method. Their inhibitory activity against several serine proteinases: bovine β-trypsin, bovine α-chymotypsin, human leukocyte
Hsiang-Ruei Liao et al.
Biochemical pharmacology, 84(2), 182-191 (2012-04-10)
Respiratory burst mediates crucial bactericidal mechanism in neutrophils. However, undesirable respiratory burst leads to pathological inflammation and tissue damage. This study investigates the effect and the underlying mechanism of 5-hydroxy-7-methoxyflavone (MCL-1), a lignan extracted from the leaves of Muntingia calabura
W Jin et al.
Oncogene, 32(15), 1978-1987 (2012-05-30)
Although the significance of cathepsin G (CTSG) in host defense has been intensively investigated, little is known about its potential roles in granulopoiesis or leukemogenesis. We report here that CTSG is directly targeted and suppressed by AML1-ETO in t(8;21) acute
Emma Lefrançais et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(5), 1673-1678 (2012-02-07)
Interleukin-33 (IL-33) (NF-HEV) is a chromatin-associated nuclear cytokine from the IL-1 family, which has been linked to important diseases, including asthma, rheumatoid arthritis, ulcerative colitis, and cardiovascular diseases. IL-33 signals through the ST2 receptor and drives cytokine production in type
A Siltari et al.
Arzneimittel-Forschung, 62(10), 477-481 (2012-08-25)
In the fermentation of milk by certain lactic acid bacteria, casein is degraded into bioactive tripeptides shown to lower blood pressure in experimental animal models and in mildly hypertensive humans. This effect is suggested to result mainly in inhibition of

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