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MAB3045

Sigma-Aldrich

Anti-Connexin 35/36 Antibody, clone 8F6.2

clone 8F6.2, Chemicon®, from mouse

Synonym(s):

Cx35/36

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

8F6.2, monoclonal

species reactivity

monkey, fish, rabbit

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

isotype

IgG1

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

rabbit ... Gjd2(100341036)

Specificity

Recognizes perch Connexin 35. Does not cross-react with Connexin 34.7, a very closely related protein. Also recognizes rabbit and macaque Connexin 36, the gene homologue of Connexin 35. Labels gap junctions in retinas of perch, rabbit and macaque in immunohistochemistry.

Application

Detect Connexin 35/36 using this Anti-Connexin 35/36 Antibody, clone 8F6.2 validated for use in IH.

Linkage

Replaces: MAB3044

Physical form

Format: Purified
Purified immunoglobulin. Liquid in 0.1M Citrate buffer with 50% glycerol, also contains 0.1% Sodium Azide as a preservative

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Elena Ivanova et al.
Frontiers in cellular neuroscience, 9, 390-390 (2015-10-21)
Retinal degeneration (RD) encompasses a family of diseases that lead to photoreceptor death and visual impairment. Visual decline due to photoreceptor cell loss is further compromised by emerging spontaneous hyperactivity in inner retinal cells. This aberrant activity acts as a
Adam C Miller et al.
eLife, 6 (2017-05-23)
Neural network function is based upon the patterns and types of connections made between neurons. Neuronal synapses are adhesions specialized for communication and they come in two types, chemical and electrical. Communication at chemical synapses occurs via neurotransmitter release whereas
Yuan-Hao Lee et al.
Bioscience and bioengineering (Boston, Mass.), 4(4), 78-84 (2018-12-01)
Calcium signals act as a ubiquitous secondary messenger in regulating many body functions. The detection of calcium microdomain signals is greatly facilitated by the existence of biomarker-targeted fluorescent probes. In this study, SRRF (super-resolution radial fluctuations) algorithm were used to
Adenosine and dopamine receptors coregulate photoreceptor coupling via gap junction phosphorylation in mouse retina.
Li, H; Zhang, Z; Blackburn, MR; Wang, SW; Ribelayga, CP; O'Brien, J
The Journal of Neuroscience null
Christopher H Emfinger et al.
Physiological reports, 7(11), e14101-e14101 (2019-06-05)
Islet β-cell membrane excitability is a well-established regulator of mammalian insulin secretion, and defects in β-cell excitability are linked to multiple forms of diabetes. Evolutionary conservation of islet excitability in lower organisms is largely unexplored. Here we show that adult

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