Skip to Content
Merck
All Photos(1)

Documents

344729

Sigma-Aldrich

1-Acetyl-3-methylpiperidine

99%

Synonym(s):

1-(3-Methyl-1-piperidinyl)-ethanone, 1-Acetyl-3-pipecoline

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C8H15NO
CAS Number:
4593-16-2
Molecular Weight:
141.21
EC Number:
224-983-2
MDL number:
MFCD00015912
UNSPSC Code:
12352100
PubChem Substance ID:
24861276
NACRES:
NA.22

Assay

99%

refractive index

n20/D 1.476 (lit.)

bp

239 °C (lit.)

mp

−15 °C (lit.)

density

0.974 g/mL at 25 °C (lit.)

SMILES string

CC1CCCN(C1)C(C)=O

InChI

1S/C8H15NO/c1-7-4-3-5-9(6-7)8(2)10/h7H,3-6H2,1-2H3

InChI key

XKFPNHDGLSYZRC-UHFFFAOYSA-N

Application

1-Acetyl-3-methylpiperidine may be employed as piperidine ligand to investigate the enzymatic activity and three-dimensional structure non-peptide ligand-cyclophilin complexes.
Reactant for:
Regioselective amidyl radical cyclization
Regioselective oxidation of cyclic amino compounds

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

224.6 °F - closed cup

Flash Point(C)

107 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

George Kontopidis et al.
Acta crystallographica. Section D, Biological crystallography, 60(Pt 3), 479-485 (2004-03-03)
Piperidine ligands are described that provide the first examples of non-peptidic ligand structures for the cyclophilin family of proteins. Crystal structures of two ligand complexes are compared with the unliganded protein and show ligand-induced changes in side-chain conformation and water

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service