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Merck

SMC3

structural maintenance of chromosomes 3

Synonyms:
BAM, BMH, CDLS3, CSPG6, HCAP, SMC3L1
Species:
UniProtKB ID:
Gene ID:
  • Human(9126) Summary: This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008]
  • Mouse(13006) structural maintenance of chromosomes 3
  • Rat(29486) structural maintenance of chromosomes 3
  • naked mole-rat(101725969) structural maintenance of chromosomes 3
  • Thale Cress(834917) structural maintenance of chromosomes protein 4
  • Zebrafish(324475) structural maintenance of chromosomes 3
  • chicken(395188) structural maintenance of chromosomes 3
  • dog(486886) structural maintenance of chromosomes 3
  • Horse(100059335) structural maintenance of chromosomes 3
  • domestic cat(101093211) structural maintenance of chromosomes 3
  • cow(281729) structural maintenance of chromosomes 3
  • sheep(101119007) structural maintenance of chromosomes 3
  • Domestic Rabbit(100354309) structural maintenance of chromosomes 3
  • domestic guinea pig(100726965) structural maintenance of chromosomes 3

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CSPG6 antibody produced in mouse, clone 1G1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Rabbit anti-SMC3 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human, mouse
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-SMC3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-CSPG6 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-SMC3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
PrEST Antigen SMC3, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse SMC3,
Species
mouse
MISSION® esiRNA, targeting human SMC3,
Species
human