RFC5
replication factor C (activator 1) 5, 36.5kDa
Synonyms:
RFC36
Species:
Human RFC5 (5985), Mouse Rfc5 (72151), Rat Rfc5 (304528), domestic cat RFC5 (101092297), Zebrafish rfc5 (445385), naked mole-rat Rfc5 (101710167), sheep RFC5 (101109740), domestic guinea pig Rfc5 (100723132), Horse RFC5 (100054946), dog RFC5 (477499) ...More
UniProtKB ID:
Gene ID:
- Human(5985) Summary: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9. [provided by RefSeq, May 2011]
- Mouse(72151) replication factor C (activator 1) 5
- Rat(304528) replication factor C (activator 1) 5
- domestic cat(101092297) replication factor C (activator 1) 5, 36.5kDa
- Zebrafish(445385) replication factor C (activator 1) 5
- naked mole-rat(101710167) replication factor C (activator 1) 5, 36.5kDa
- sheep(101109740) replication factor C (activator 1) 5, 36.5kDa
- domestic guinea pig(100723132) replication factor C (activator 1) 5, 36.5kDa
- Horse(100054946) replication factor C (activator 1) 5, 36.5kDa
- dog(477499) replication factor C (activator 1) 5, 36.5kDa
- cow(508389) replication factor C (activator 1) 5, 36.5kDa
- Domestic Rabbit(100345366) replication factor C (activator 1) 5, 36.5kDa
- chicken(100859719) replication factor C (activator 1) 5, 36.5kDa
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-RFC5 antibody produced in mouse, clone 1B1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-RFC5 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-RFC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Product Number
Description
Species
PrEST Antigen RFC5, Prestige Antigens™ Powered by Atlas Antibodies, buffered aqueous solution,
Species
human