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Merck

PSMD13

proteasome (prosome, macropain) 26S subunit, non-ATPase, 13

Synonyms:
HSPC027, Rpn9, S11, p40.5
Species:
UniProtKB ID:
Gene ID:
  • Human(5719) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(23997) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
  • Rat(365388) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
  • domestic guinea pig(100714436) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
  • naked mole-rat(101698107) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
  • sheep(101104945) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
  • cow(513525) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
  • Horse(100050948) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
  • domestic cat(101101591) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
  • dog(475934) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
  • chicken(422990) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
  • Zebrafish(393922) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PSMD13 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-PSMD13 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PSMD13 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-PSMD13 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
PrEST Antigen PSMD13, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Psmd13,
Species
mouse
MISSION® esiRNA, targeting human PSMD13,
Species
human