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Merck

NOX4

NADPH oxidase 4

Synonyms:
KOX, KOX-1, RENOX
Species:
UniProtKB ID:
Gene ID:
  • Human(50507) Summary: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
  • Mouse(50490) NADPH oxidase 4
  • Rat(85431) NADPH oxidase 4
  • domestic guinea pig(100727664) NADPH oxidase 4
  • naked mole-rat(101726508) NADPH oxidase 4
  • chicken(419012) NADPH oxidase 4
  • dog(485144) NADPH oxidase 4
  • cow(378474) NADPH oxidase 4
  • sheep(100034665) NADPH oxidase 4
  • Domestic Rabbit(100339697) NADPH oxidase 4
  • Horse(100050321) NADPH oxidase 4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NOX4 Antibody, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
Anti-NOX4 Antibody, clone 10A8.1, culture supernatant, clone 10A8.1, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
ANTI-NOX4 (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti- NOX4 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-NADPH oxidase 4 (NOX4) Antibody, clone 6Q3U8, Rabbit Monoclonal, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Nox4,
Species
mouse
MISSION® esiRNA, targeting human NOX4,
Species
human