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Merck

NLRP10

NLR family, pyrin domain containing 10

Synonyms:
CLR11.1, NALP10, NOD8, PAN5, PYNOD
Species:
UniProtKB ID:
Gene ID:
  • Human(338322) Summary: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq, Jul 2008]
  • Mouse(244202) NLR family, pyrin domain containing 10
  • Rat(293426) NLR family, pyrin domain containing 10
  • dog(611323) NLR family, pyrin domain containing 10
  • Horse(100070865) NLR family, pyrin domain containing 10
  • domestic cat(101089644) NLR family, pyrin domain containing 10
  • naked mole-rat(101702326) NLR family, pyrin domain containing 10

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NLRP10 Antibody, clone 8H2, clone 8H2, from rat,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry

western blot
Anti-NLRP10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-NLRP10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-NALP10 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
PrEST Antigen NLRP10, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human
PrEST Antigen NLRP10, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NLRP10,
Species
human
MISSION® esiRNA, targeting mouse Nlrp10,
Species
mouse