EXOC2
exocyst complex component 2
Synonyms:
SEC5, SEC5L1, Sec5p
Species:
Human EXOC2 (55770), Mouse Exoc2 (66482), Rat Exoc2 (171455), dog EXOC2 (478696), naked mole-rat Exoc2 (101705272), domestic cat EXOC2 (101089188), sheep EXOC2 (101110975), Domestic Rabbit EXOC2 (100354138), chicken EXOC2 (420889), cow EXOC2 (513431) ...More
UniProtKB ID:
Gene ID:
- Human(55770) Summary: The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
- Mouse(66482) exocyst complex component 2
- Rat(171455) exocyst complex component 2
- dog(478696) exocyst complex component 2
- naked mole-rat(101705272) exocyst complex component 2
- domestic cat(101089188) exocyst complex component 2
- sheep(101110975) exocyst complex component 2
- Domestic Rabbit(100354138) exocyst complex component 2
- chicken(420889) exocyst complex component 2
- cow(513431) exocyst complex component 2
- domestic guinea pig(100714267) exocyst complex component 2
- Zebrafish(100004870) exocyst complex component 2
- Horse(100049898) exocyst complex component 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-EXOC2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence