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Merck

CD3E

CD3e molecule, epsilon (CD3-TCR complex)

Synonyms:
T3E, TCRE
Species:
UniProtKB ID:
Gene ID:
  • Human(916) Summary: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
  • Mouse(12501) CD3 antigen, epsilon polypeptide
  • Rat(315609) CD3 molecule, epsilon
  • domestic cat(493936) CD3e molecule, epsilon (CD3-TCR complex)
  • naked mole-rat(101711464) CD3e molecule, epsilon (CD3-TCR complex)
  • dog(442981) CD3e molecule, epsilon (CD3-TCR complex)
  • sheep(443437) CD3e molecule, epsilon (CD3-TCR complex)
  • Domestic Rabbit(100008616) CD3e molecule, epsilon (CD3-TCR complex)
  • domestic guinea pig(100727781) CD3e molecule, epsilon (CD3-TCR complex)
  • cow(281054) CD3e molecule, epsilon (CD3-TCR complex)
  • chicken(396062) CD3e molecule, epsilon (CD3-TCR complex)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CD3E antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-CD3E antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Monoclonal Anti-CD3-APC antibody produced in mouse, clone APA1/1,
Species Reactivity
Application
flow cytometry
Monoclonal Anti-CD3-APC antibody produced in mouse, clone OKT3,
Species Reactivity
Application
flow cytometry
Anti-CD3E antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM344, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry

Proteins

Product Number
Description
Species
CD3E human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Cd3e,
Species
mouse
MISSION® esiRNA, targeting human CD3E,
Species
human