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Merck

CACNB2

calcium channel, voltage-dependent, beta 2 subunit

Synonyms:
CACNLB2, CAVB2, MYSB
Species:
Human CACNB2 (783), Mouse Cacnb2 (12296), Rat Cacnb2 (116600), domestic guinea pig Cacnb2 (100192393), naked mole-rat Cacnb2 (101713647), Domestic Rabbit CACNB2 (100009277), cow CACNB2 (327667), sheep CACNB2 (101112498), dog CACNB2 (487113), domestic cat CACNB2 (101093028) ...More
UniProtKB ID:
Q08289, A6PVM5, A6PVM7, A6PVM8, O00304, Q5VVG9, Q5VVH0, Q5VWV6
Gene ID:
  • Human(783) Summary: This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Feb 2013]
  • Mouse(12296) calcium channel, voltage-dependent, beta 2 subunit
  • Rat(116600) calcium channel, voltage-dependent, beta 2 subunit
  • domestic guinea pig(100192393) calcium channel, voltage-dependent, beta 2 subunit
  • naked mole-rat(101713647) calcium channel, voltage-dependent, beta 2 subunit
  • Domestic Rabbit(100009277) calcium channel, voltage-dependent, beta 2 subunit
  • cow(327667) calcium channel, voltage-dependent, beta 2 subunit
  • sheep(101112498) calcium channel, voltage-dependent, beta 2 subunit
  • dog(487113) calcium channel, voltage-dependent, beta 2 subunit
  • domestic cat(101093028) calcium channel, voltage-dependent, beta 2 subunit
  • Horse(100055971) calcium channel, voltage-dependent, beta 2 subunit
  • chicken(428420) calcium channel, voltage-dependent, beta 2 subunit

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Small Molecule - Allosteric Modulator

Product Number
Description
Species
PHR1049
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
1287303
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Species
human
Y0001805
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Species
human
Y0001280
Gabapentin, European Pharmacopoeia (EP) Reference Standard,
Species
human
G154
Gabapentin, solid,
Species
human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
SAB1403628
Monoclonal Anti-CACNB2 antibody produced in mouse, clone 6C4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
western blot
WH0000783M1
Monoclonal Anti-CACNB2 antibody produced in mouse, clone 6C1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
SAB5200044
Monoclonal Anti-CACNB2 antibody produced in mouse, clone S8B-1, 1 mg/mL, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
AB5787
Anti-Calcium Channel β 2 Antibody, near CT, Chemicon®, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot
SAB2100330
Anti-CACNB2 (ab1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot

Small Molecule - Blocker

Product Number
Description
Species
B5016
Bepridil hydrochloride, powder,
Species
human
T4577
Terodiline hydrochloride, ≥98% (HPLC), solid,
Species
human

esiRNA

Product Number
Description
Species
EHU124941
MISSION® esiRNA, targeting human CACNB2,
Species
human
EMU059501
MISSION® esiRNA, targeting mouse Cacnb2,
Species
mouse