ATF1
activating transcription factor 1
Synonyms:
EWS-ATF1, FUS/ATF-1, TREB36
Species:
Human ATF1 (466), Mouse Atf1 (11908), Rat Atf1 (315305), naked mole-rat Atf1 (101726719), cow ATF1 (506967), sheep ATF1 (101117917), domestic cat ATF1 (101088253), Zebrafish atf1 (325609), chicken ATF1 (426873), domestic guinea pig Atf1 (100719533)
UniProtKB ID:
Gene ID:
- Human(466) Summary: This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq, Aug 2010]
- Mouse(11908) activating transcription factor 1
- Rat(315305) activating transcription factor 1
- naked mole-rat(101726719) activating transcription factor 1
- cow(506967) activating transcription factor 1
- sheep(101117917) activating transcription factor 1
- domestic cat(101088253) activating transcription factor 1
- Zebrafish(325609) activating transcription factor 1
- chicken(426873) activating transcription factor 1
- domestic guinea pig(100719533) activating transcription factor 1
- dog(486545) activating transcription factor 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ATF1 antibody produced in mouse, clone 3E7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ATF1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, guinea pig, horse, human, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-ATF1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-phospho-ATF1 (pSer63) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-ATF-1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
microarray
western blot
western blot