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• Flyer: Ascentis^®Express PCS-C18, 2.7 µm U/HPLC Columns

  The Ascentis^® Express PCS-C18 columns are designed for effective separation of basic, acidic, or neutral compounds using low ionic strength (formic acid) mobile phase conditions.

• Brochure: HPLC Column Selection Guide

  The comprehensive Supelco^® portfolio of analytical solutions to meet your U/HPLC and LC-MS needs.

• Brochure: HPLC Method Development Guide

  High performance liquid chromatography (HPLC) is a technique for separating analytes dissolved in a liquid, mobile phase by using their specific interaction with a stationary phase (chromatography column).

• Brochure: Ascentis^® Express Columns

  Based on Fused-Core^® particle technology, Ascentis^® Express columns provide a exceptional advancements in HPLC column performance and the benefits of high sample throughput at maximum resolution.

• Brochure: BIOshell™ Columns

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• Brochure: Chromolith^® HPLC Columns

  To truly accelerate chromatographic separations, there is no better choice than Chromolith® HPLC columns. Due to their revolutionary, monolithic technology, Chromolith® columns provide excellent and rapid separations with extremely high robustness and matrix tolerance compared to particulate columns.

• Brochure: Purospher STAR Columns

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• Brochure: Chiral HPLC Columns

  Columns for versatile and robust Chiral HPLC and LC-MS separations.

• Brochure: HPLC Accessories

  The use of HPLC systems to achieve faster analyses and increased resolution pushes systems toward higher operating pressures. For instance, faster flow rates, longer column lengths, and reduced particle sizes gain a performance advantage in HPLC, but at a cost of increased operating pressures.

• Brochure: Discovery Bio Columns

  Many of the challenges facing researchers in the proteomics and biopharmaceutical fields are related to the need to obtain as much information as possible on very limited samples. We designed Discovery^® BIO Wide Pore reversed-phase HPLC columns to address these challenges.

• Brochure: LC-MS Resource Guide

  In this guide, we provide a premier selection of proven Supelco^® tools and consumables that meet the requirements of scientists who primarily use the LC-MS technique for analysis of drugs, biomolecules separation and analytical assays.

• Brochure: LC-MS Contaminants

  In this technical bulletin, you will learn some tips on identifying LC-MS contaminants and avoiding contamination. Our 110 years of separation expertise, combined with our precision-manufactured products, give you the greatest chance of obtaining reproducible, clean data.

• Application Note: Supelco^® HPLC Products: The Best Choice for Any LC Instrument

  Since the 1970’s, Supelco^® has been a trusted name in high performance liquid chromatography (HPLC) consumables. From a diverse array of columns packed with different stationary phases to a complete portfolio of HPLC accessories, the Supelco^® portfolio of HPLC consumables caters to the needs of all analysts.

• Application Guide: Drug of Abuse

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• HPLC Method Transfer Calculator

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• Wall Chart: HPLC Packings for USP Compendial Methods

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• Application Guide: Ascentis^® Express and BIOshell™ Column Cleaning Procedures and Best Practices

  To maximize the lifetime of an HPLC column and ensure its top performance, it is necessary to properly maintain the column. Many different factors can contribute to loss of resolution or sensitivity, but often times the following factors lead to the vast majority of column performance issues.