- Comparative evaluation of determination of beta-lactam intermediates.
Comparative evaluation of determination of beta-lactam intermediates.
Hindustan antibiotics bulletin (1993-08-01)
B S Deshpande, S S Ambedkar, J G Shewale
PMID7960926
ABSTRACT
The Schiff's base formation between 6-aminopenicillanic acid, 7-aminodesacetoxycephalosporanic acid and 7-aminocephalosporanic acid and p-dimethylaminobenzaldehyde (PDAB) was investigated. The factors that affect the reaction such as concentration of PDAB, time and pH were studied and optimised for estimation of these intermediates.
MATERIALS
Product Number
Brand
Product Description
Sigma-Aldrich
4-(Dimethylamino)benzaldehyde, puriss. p.a., reag. Ph. Eur., ≥99% (perchloric acid titration)
Sigma-Aldrich
4-(Dimethylamino)benzaldehyde, suitable for histochemical demonstration of nitro blue tetrazolium reduction in neutrophils