- A cis amide bond surrogate incorporating 1,2,4-triazole.
A cis amide bond surrogate incorporating 1,2,4-triazole.
The Journal of organic chemistry (2002-05-11)
Yukio Hitotsuyanagi, Shuichi Motegi, Haruhiko Fukaya, Koichi Takeya
PMID12003534
ABSTRACT
A novel cis amide bond surrogate incorporating 1,2,4-triazole was designed and synthesized by the reaction of a thionotripeptide, formic hydrazide, and mercury(II) acetate. This method of surrogate formation was also applicable to a cyclic thionopeptide.
MATERIALS