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SML3061

Sigma-Aldrich

BSJ-04-122

>97% (HPLC)

Synonym(s):

N-(2-((5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)phenyl)acrylamide

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5 MG
€88.40
25 MG
€285.00

€88.40


Estimated to ship on23 April 2025


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5 MG
€88.40
25 MG
€285.00

About This Item

Empirical Formula (Hill Notation):
C15H12ClN5O
CAS Number:
Molecular Weight:
313.74
UNSPSC Code:
12352200
NACRES:
NA.77

€88.40


Estimated to ship on23 April 2025


Request a Bulk Order

Quality Level

Assay

>97% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

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Show Differences

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This Item
SML3062SML3475SML3567
EN450 ≥98% (HPLC)

SML3567

EN450

assay

>97% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

white to beige

color

white to beige

color

-

Biochem/physiol Actions

BSJ-04-122 is a cell penetrant, potent and selective covalent inhibitor of MKK4 and MKK7 (MAP2K4/7) that binds to Cys247 of MKK4. It potently inhibits JNK phosphorylation. BSJ-04-122 exhibits antiproliferative effects against triple-negative breast cancer cells. Also, BSJ-04-122 enhances antiproliferative activity of JNK-IN-8.
cell penetrant, potent and selective covalent inhibitor of MKK4 and MKK7 (MAP2K4/7)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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