AB5372
Anti-Trk B Antibody, pain, a.a. 54-67 rTrkB
serum, Chemicon®
Synonym(s):
BDNF/NT-3 Growth Factors Receptor, Tyrosine Kinase Receptor B
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat, human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... NTRK2(4915)
Specificity
TrkB. The sequence used for the immunogen was chosen to avoid cross reactivity with trkA or trkC.
Immunogen
A synthetic peptide from rat trkB
Epitope: a.a. 54-67 rtrkB
Application
Anti-Trk B Antibody, pain, a.a. 54-67 rTrkB detects level of Trk B & has been published & validated for use in IH & WB.
Immunohistochemistry: 1:2,000-1:3,000. The antibody reacts well with tissue from the rat spinal cord.
Immunoblotting: 1:1,000-1:1,500 on rat membrane preparations. The antibody should be
evaluated for use in Western blot by the end user. Its utility will be dependant on the level of
the protein expressed in the tissues or cells being tested.
Optimal working dilutions must be determined by end user.
Immunoblotting: 1:1,000-1:1,500 on rat membrane preparations. The antibody should be
evaluated for use in Western blot by the end user. Its utility will be dependant on the level of
the protein expressed in the tissues or cells being tested.
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
Neurochemistry & Neurotrophins
Physical form
Rabbit serum. Lyophilized. Contains no preservative. Reconstitute with 50 μL of sterile distilled water. Centrifuge if necessary to remove any residue.
Storage and Stability
Maintain lyophilized material at -20°C to -70°C for up to 6 months after date of receipt. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Zitao Zhang et al.
Molecular medicine reports, 15(3), 1362-1367 (2017-01-19)
Brain‑derived neurotrophic factor (BDNF), a member of the neurotropic family, is expressed in osteoblast‑like cells of a fracture callus, however, its role in fracture healing remains to be fully elucidated. Osteoblasts isolated from Sprague Dawley rats were stimulated by BDNF
Laurens W J Bosman et al.
Brain cell biology, 35(1), 87-101 (2007-10-18)
The receptor tyrosine kinase TrkB and its ligands, brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5), are critically important for growth, survival and activity-dependent synaptic strengthening in the central nervous system. These TrkB-mediated actions occur in a highly cell-type specific manner.
Rita Machaalani et al.
Neurotoxicology, 74, 40-46 (2019-05-24)
Cigarette smoke exposure during pregnancy into infancy affects brain growth and development in both short and long term (into adulthood). Using a mouse model of pre- into post- natal cigarette smoke exposure (SE), we aimed to determine the effects on
Ji Min Yu et al.
Methods in molecular biology (Clifton, N.J.), 702, 219-231 (2010-11-18)
While adult stem cells can be induced to transdifferentiate into multiple lineages of cells or tissues, their plasticity and utility for human therapy remains controversial. In this chapter, we describe methods for the transdifferentiation of human adipose tissue-derived stem cells
Amy A Robinson et al.
GeroScience, 40(1), 31-47 (2018-01-23)
Mammalian aging is associated with decline in cognitive functions. Studies searching for a cause of cognitive aging initially focused on neuronal loss but quantitative investigations of rat, monkey, and human brain using stereology demonstrated that in normal aging, unlike in
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