938882

NanoFabTx Polymers for Microneedles

Hyaluronic acid sodium salt

• Synonym(s): Hyaluronic acid sodium salt
• Linear Formula: (C₁₄H₂₁NaNO₁₁)_n
• CAS Number: 9067-32-7
• MDL number: MFCD01773053

Properties

• Quality Level: 100
• Assay: ≥90%
• mol wt: 100-150 kDa
• storage temp.: 2-8°C
• SMILES string: O[C@H]1[C@H](O[C@@H]2O[C@H](C(O[Na])=O)[C@@H](OC)[C@H](O)[C@H]2O)[C@@H](NC(C)=O)[C@H](C)O[C@@H]1CO

Description

Application

NanoFabTx^™ Polymers for Microneedles are carefully selected polymers that can be used to formulate microneedle patches. Microneedles are tiny projections of needles approximately 400-800um in length arranged in a small 1cm x 1cm patch. Microneedles are composed of blends of synthetic or natural polymers at suitable concentrations. Sodium hyaluronic acid (HA) is the derivate of a natural polymer and is a natural polysaccharide. It is a water-soluble polymer and is available in different molecular weights. The formation of the microneedles depends on the molecular weight and concentration of HA.


The NanoFabTx^™ Polymers for Microneedles can be used with the microneedle templates to formulate microneedle that can be used for several applications, such as delivering various therapeutic molecules and vaccine antigens via the skin. The selected polymer will enable users to:

1)save time in selecting the polymer and provide a starting point to formulate microneedles by avoiding lengthy trial-and-error optimization.

2)formulate microneedles for various drug delivery applications.

Legal Information

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable