TPH1
tryptophan hydroxylase 1
Synonyms:
TPRH, TRPH
Species:
Human TPH1 (7166), Mouse Tph1 (21990), Rat Tph1 (24848), chicken TPH1 (395799), naked mole-rat Tph1 (101710219), domestic guinea pig Tph1 (100718189), sheep TPH1 (101113620), Domestic Rabbit TPH1 (100101558), Horse TPH1 (100056614), cow TPH1 (781941) ...More
UniProtKB ID:
Gene ID:
- Human(7166) Summary: This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009]
- Mouse(21990) tryptophan hydroxylase 1
- Rat(24848) tryptophan hydroxylase 1
- chicken(395799) tryptophan hydroxylase 1
- naked mole-rat(101710219) tryptophan hydroxylase 1
- domestic guinea pig(100718189) tryptophan hydroxylase 1
- sheep(101113620) tryptophan hydroxylase 1
- Domestic Rabbit(100101558) tryptophan hydroxylase 1
- Horse(100056614) tryptophan hydroxylase 1
- cow(781941) tryptophan hydroxylase 1
- dog(611956) tryptophan hydroxylase 1
- domestic cat(101098575) tryptophan hydroxylase 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TPH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Tryptophan Hydroxylase antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Tryptophan Hydroxylase/Tyrosine Hydroxylase/Phenylalanine Hydroxylase Antibody, clone PH8, clone PH8, Chemicon®, from mouse,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Tryptophan Hydroxylase Antibody, Chemicon®, from sheep,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Anti-phospho-Tryptophan Hydroxylase (pSer58) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Small Molecule - Precursor
Product Number
Description
Species