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Merck

TM2D1

TM2 domain containing 1

Synonyms:
BBP
Species:
UniProtKB ID:
Gene ID:
  • Human(83941) Summary: The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. [provided by RefSeq, Dec 2008]
  • Mouse(94043) TM2 domain containing 1
  • Rat(362545) TM2 domain containing 1
  • domestic guinea pig(100722312) TM2 domain containing 1
  • dog(479551) TM2 domain containing 1
  • cow(514249) TM2 domain containing 1
  • naked mole-rat(101721201) TM2 domain containing 1
  • chicken(775978) TM2 domain containing 1
  • domestic cat(101080393) TM2 domain containing 1
  • Zebrafish(100093710) TM2 domain containing 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TM2D1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-TM2D1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TM2D1,
Species
human