PCDHA9

protocadherin alpha 9

Synonyms:

PCDH-ALPHA9

Species:

UniProtKB ID:

Gene ID:

Human(9752) Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
Mouse(192161) protocadherin alpha 9
Rat(393090) protocadherin alpha 9
domestic guinea pig(100714706) protocadherin alpha 9
chicken(497219) protocadherin alpha 9
dog(487165) protocadherin alpha 9
cow(539540) protocadherin alpha 9
cow(616121) protocadherin alpha 9

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Product Number

Description

Species Reactivity

Application

Monoclonal Anti-PCDHA9 antibody produced in mouse, clone 3C1, purified immunoglobulin, buffered aqueous solution,

Species Reactivity

human

Application

ELISA
western blot