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Merck

NLRP10

NLR family, pyrin domain containing 10

Synonyms:
CLR11.1, NALP10, NOD8, PAN5, PYNOD
Species:
UniProtKB ID:
Gene ID:
  • Human(338322) Summary: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq, Jul 2008]
  • Mouse(244202) NLR family, pyrin domain containing 10
  • Rat(293426) NLR family, pyrin domain containing 10
  • dog(611323) NLR family, pyrin domain containing 10
  • Horse(100070865) NLR family, pyrin domain containing 10
  • domestic cat(101089644) NLR family, pyrin domain containing 10
  • naked mole-rat(101702326) NLR family, pyrin domain containing 10

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NLRP10 Antibody, clone 8H2, clone 8H2, from rat,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry

western blot
Anti-NLRP10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-NLRP10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-NALP10 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NLRP10,
Species
human
MISSION® esiRNA, targeting mouse Nlrp10,
Species
mouse