LILRB4
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
Synonyms:
CD85K, ILT-3, ILT3, LIR-5, LIR5
Species:
Human LILRB4 (11006), Mouse Lilrb4 (14728), Rat Lilrb4 (292594), domestic guinea pig Lilrb4 (100720776)
UniProtKB ID:
Gene ID:
- Human(11006) Summary: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(14728) leukocyte immunoglobulin-like receptor, subfamily B, member 4
- Rat(292594) leukocyte immunoglobulin-like receptor, subfamily B, member 4
- domestic guinea pig(100720776) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-LILRB4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunofluorescence
esiRNA
Product Number
Description
Species