KLHL3
kelch-like family member 3
Synonyms:
PHA2D
Species:
Human KLHL3 (26249), Mouse Klhl3 (100503085), Rat Klhl3 (498697), domestic guinea pig Klhl3 (100732587), naked mole-rat Klhl3 (101699865), sheep KLHL3 (101107091), Horse KLHL3 (100062564), cow KLHL3 (533364), Domestic Rabbit KLHL3 (100343290), domestic cat KLHL3 (101083647) ...More
UniProtKB ID:
Gene ID:
- Human(26249) Summary: This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012]
- Mouse(100503085) kelch-like 3
- Rat(498697) kelch-like family member 3
- domestic guinea pig(100732587) kelch-like family member 3
- naked mole-rat(101699865) kelch-like family member 3
- sheep(101107091) kelch-like 3 (Drosophila)
- Horse(100062564) kelch-like 3 (Drosophila)
- cow(533364) kelch-like family member 3
- Domestic Rabbit(100343290) kelch-like 3 (Drosophila)
- domestic cat(101083647) kelch-like 3 (Drosophila)
- Zebrafish(568556) kelch-like 3 (Drosophila)
- chicken(416303) kelch-like 3 (Drosophila)
- dog(481523) kelch-like 3 (Drosophila)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-KLHL3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-KLHL3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rat
Application
western blot
Anti-KLHL3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-KLHL3 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human, rabbit
Application
western blot
esiRNA
Product Number
Description
Species