Skip to Content
Merck

FBL

fibrillarin

Synonyms:
FIB, FLRN, RNU3IP1
Species:
UniProtKB ID:
Gene ID:
  • Human(2091) Summary: This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008]
  • Mouse(14113) fibrillarin
  • Rat(292747) fibrillarin
  • fruit fly(46234) fumble
  • Zebrafish(406275) fibrillarin
  • dog(476460) fibrillarin
  • domestic cat(101094807) fibrillarin
  • cow(538548) fibrillarin
  • sheep(101117097) fibrillarin
  • naked mole-rat(101716171) fibrillarin
  • domestic guinea pig(100722585) fibrillarin

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-FBL antibody produced in mouse, clone 4G9-E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Monoclonal Anti-FBL antibody produced in mouse, clone 3E10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-Fibrillarin/U3 RNP antibody produced in rabbit, ,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
Anti-Fibrillarin Antibody, clone 38F3, clone 38F3, from mouse,
Species Reactivity
drosophila, human, mouse, rat, yeast
Application
immunocytochemistry
western blot
Anti-FBL antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, guinea pig, horse, human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Fbl,
Species
mouse
MISSION® esiRNA, targeting human FBL,
Species
human