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Merck

CST3

cystatin C

Synonyms:
ARMD11
Species:
UniProtKB ID:
Gene ID:
  • Human(1471) Summary: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. [provided by RefSeq, Jul 2008]
  • Mouse(13010) cystatin C
  • Rat(25307) cystatin C
  • cow(281102) cystatin C
  • sheep(101104079) cystatin C
  • domestic cat(100462660) cystatin C
  • chicken(396497) cystatin C
  • Zebrafish(791878) cystatin C (amyloid angiopathy and cerebral hemorrhage)
  • Domestic Rabbit(100009450) cystatin C

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ELISA

Product Number
Description
Species
Rat Cst3 / Cystatin-C ELISA Kit, ,
Species
rat
Human Cystatin C ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Mouse Cystatin C ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CST3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-CST3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-CST3 antibody produced in mouse, clone 3D10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Monoclonal Anti-CST3 antibody produced in mouse, clone 2G4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Monoclonal Anti-CST3 antibody produced in mouse, clone 1H4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

Proteins

Product Number
Description
Species
SILuProt CST3, Cystatin C human, recombinant, expressed in E. coli, SIL MS Protein Standard, 15N-labeled,
Species
human
SILuLite CST3, Cystatin C human, recombinant, expressed in E. coli, MS Protein Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CST3,
Species
human
MISSION® esiRNA, targeting mouse Cst3,
Species
mouse