CDKN1C
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
Synonyms:
BWCR, BWS, KIP2, WBS, p57, p57Kip2
Species:
Human CDKN1C (1028), Mouse Cdkn1c (12577), Rat Cdkn1c (246060), sheep CDKN1C (100216434), naked mole-rat Cdkn1c (101726530), cow CDKN1C (510972), Zebrafish cdkn1c (399483)
UniProtKB ID:
Gene ID:
- Human(1028) Summary: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
- Mouse(12577) cyclin-dependent kinase inhibitor 1C (P57)
- Rat(246060) cyclin-dependent kinase inhibitor 1C
- sheep(100216434) cyclin-dependent kinase inhibitor 1C (p57, Kip2)
- naked mole-rat(101726530) cyclin-dependent kinase inhibitor 1C (p57, Kip2)
- cow(510972) cyclin-dependent kinase inhibitor 1C (p57, Kip2)
- Zebrafish(399483) cyclin-dependent kinase inhibitor 1C
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CDKN1C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Kip2 Antibody, Upstate®, from rabbit,
Species Reactivity
bovine, human
Application
immunoprecipitation (IP)
western blot
western blot
Anti-p57 KIP2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-p57Kip2 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
bovine, human, mouse
Application
immunoprecipitation (IP)
western blot
western blot
Small Molecule - Inhibitor
esiRNA
Product Number
Description
Species