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Merck

ALOX5AP

arachidonate 5-lipoxygenase-activating protein

Synonyms:
FLAP
Species:
UniProtKB ID:
Gene ID:
  • Human(241) Summary: This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(11690) arachidonate 5-lipoxygenase activating protein
  • Rat(29624) arachidonate 5-lipoxygenase activating protein
  • Horse(100034178) arachidonate 5-lipoxygenase-activating protein
  • cow(613869) arachidonate 5-lipoxygenase-activating protein
  • dog(477323) arachidonate 5-lipoxygenase-activating protein
  • domestic guinea pig(100733727) arachidonate 5-lipoxygenase-activating protein
  • chicken(770904) arachidonate 5-lipoxygenase-activating protein
  • naked mole-rat(101704126) arachidonate 5-lipoxygenase-activating protein
  • domestic cat(101090316) arachidonate 5-lipoxygenase-activating protein
  • Zebrafish(337376) arachidonate 5-lipoxygenase-activating protein

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ALOX5AP (C-term) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry

western blot
Anti-ALOX5AP (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-ALOX5AP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-FLAP/ALOX5AP, C-Terminal antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
flow cytometry

immunofluorescence

immunohistochemistry

western blot
Anti-FLAP/ALOX5AP (Internal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human
Application
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
BW B70C, >98% (HPLC), solid,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Alox5ap,
Species
mouse
MISSION® esiRNA, targeting human ALOX5AP,
Species
human