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Merck

1563003

USP

Probenecid

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

p-(Dipropylsulfamoyl)-benzoesäure

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200 MG

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€ 407,00


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Über diesen Artikel

Empirische Formel (Hill-System):
C13H19NO4S
CAS-Nummer:
Molekulargewicht:
285.36
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:

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Unterstützung erhalten

grade

pharmaceutical primary standard

API family

probenecid

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O

InChI

1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)

InChI key

DBABZHXKTCFAPX-UHFFFAOYSA-N

Gene Information

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Dieser Artikel
P3000000P87611564006
Probenecid United States Pharmacopeia (USP) Reference Standard

USP

1563003

Probenecid

Probenecid European Pharmacopoeia (EP) Reference Standard

P3000000

Probenecid

Probenecid

P8761

Probenecid

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

-

grade

pharmaceutical primary standard

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

-

format

neat

API family

probenecid

API family

probenecid

API family

-

API family

procaine

Gene Information

human ... SLC22A11(55867), SLC22A6(9356), SLC22A8(9376)

Gene Information

human ... SLC22A11(55867), SLC22A6(9356), SLC22A8(9376)

Gene Information

human ... SLC22A11(55867), SLC22A6(9356), SLC22A8(9376)

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Probenecid USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Probenecid and Colchicine Tablets
  • Probenecid Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Comparable product

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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Lagerklasse

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable


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Analysenzertifikate (COA)

Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

Clinical pharmacokinetics of probenecid.
Cunningham, R. F., Z. H. Israili, and P. G. Dayton.
Clinical Pharmacokinetics, 6.2, 135-151 (1981)
Probenecid and zidovudine metabolism.
Kornhauser, DavidM, et al.
Lancet, 334.8661, 473-475 (1989)
Wei Kong et al.
American journal of physiology. Heart and circulatory physiology, 307(1), H73-H79 (2014-05-06)
Previous experiments in cultures of neonatal rat myocytes demonstrated that the shape of Cai(2+) transients measured using high-affinity Ca(2+)-sensitive dyes may be misrepresented. The purpose of this study was to examine the role of dye affinity in Cai(2+) measurements in
R F Cunningham et al.
Clinical pharmacokinetics, 6(2), 135-151 (1981-03-01)
A review of the clinical applications and of the disposition of probenecid in man, including drug interactions, is presented. Probenecid is the classical competitive inhibitor of organic acid transport in the kidney and other organs. There are 2 primary clinical
Nathan Robbins et al.
Cardiovascular toxicology, 12(1), 1-9 (2011-09-23)
Probenecid was initially developed with the goal of reducing the renal excretion of antibiotics, specifically penicillin. It is still used for its uricosuric properties in the treatment in gout, but its clinical relevance has sharply fallen and is rarely used

Global Trade Item Number

SKUGTIN
1563003-200MG04061833854112

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