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Merck

1011029

USP

Acitretin-verwandte Verbindung B

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

Ethyl-all-trans-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoat, Etretinat

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20 MG
€ 1.140,00

€ 1.140,00


Voraussichtliches Versanddatum02. Juni 2025


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20 MG
€ 1.140,00

About This Item

Empirische Formel (Hill-System):
C23H30O3
CAS-Nummer:
Molekulargewicht:
354.48
MDL-Nummer:
UNSPSC-Code:
41116107
NACRES:
NA.24

€ 1.140,00


Voraussichtliches Versanddatum02. Juni 2025


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Qualität

pharmaceutical primary standard

API-Familie

acitretin

Hersteller/Markenname

USP

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

SMILES String

O(C)c1c(c(c(c(c1)C)\C=C\C(=C\C=C\C(=C\C(=O)OCC)\C)\C)C)C

InChI

1S/C23H30O3/c1-8-26-23(24)14-17(3)11-9-10-16(2)12-13-21-18(4)15-22(25-7)20(6)19(21)5/h9-15H,8H2,1-7H3/b11-9+,13-12+,16-10+,17-14+

InChIKey

HQMNCQVAMBCHCO-DJRRULDNSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Acitretin Related Compound B USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Acitretin

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Signalwort

Danger

Gefahreneinstufungen

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1A - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

Shigeyoshi Tsuji et al.
Clinical orthopaedics and related research, 468(4), 1173-1177 (2009-08-07)
Abnormal reactions accompanied by bone formation in the osteoarticular region induced by long-term administration of etretinate have been reported. We treated a patient who received continuous treatment of psoriatic erythroderma with etretinate for 7 years, and who had an osseous
H-D Park et al.
International journal of clinical pharmacology and therapeutics, 47(7), 476-482 (2009-07-31)
Acitretin is used for the treatment of psoriasis. The purpose of this study was to validate an HPLC method for the determination of acitretin and etretinate and to investigate the pharmacokinetic characteristics of acitretin in healthy Korean subjects. Plasma samples
Emiko Akasaka et al.
The Journal of dermatology, 40(4), 238-243 (2013-01-22)
Various therapies have been tried for psoriasis. In Japan, biologics began to be used for psoriasis treatment in January 2010. Their clinical efficacy is well known, but biologics cannot be used in all psoriasis patients for reasons such as side-effects
Psoriasis verrucosa.
Kenya Wakamatsu et al.
The Journal of dermatology, 37(12), 1060-1062 (2010-11-19)
Hyung-Doo Park et al.
Transfusion, 48(11), 2395-2400 (2008-07-29)
Acitretin and etretinate are potentially teratogenic. Many people taking acitretin for psoriasis have donated blood during the deferral period in Korea. Therefore, many of the blood products from these donors treated with acitretin have been circulated in Korea. A high-performance

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