SAB5703037

Anti-Phospho-BRD4(pSer1083) Antibody, clone 5B6X4, Rabbit Monoclonal

• Synonym(e): BRD4, CAP, HUNK1, HUNKI, MCAP, bromodomain containing 4
• UNSPSC-Code: 12352203
• NACRES: NA.46

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Materialien: colorless
• Klon: 5B6X4, monoclonal
• Form: liquid
• Mol-Gew.: 200 kDa
• Speziesreaktivität: human
• Konzentration: 1mg/mL
• Methode(n): western blot: 1:100 - 1:500
• Farbe: colorless
• Isotyp: IgG
• Immunogene Sequenz: HQSPP
• UniProt-Hinterlegungsnummer: O60885
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... BRD4(23476)

Beschreibung

Allgemeine Beschreibung

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.

Immunogen

A synthetic phosphorylated peptide around S1083 of human BRD4 (NP_490597.1).

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Anwendung

WB

Sicherheitshinweise

• Piktogramme: GHS07,GHS09
• Signalwort: Warning
• H-Sätze: H317,H411
• P-Sätze: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Gefahreneinstufungen: Aquatic Chronic 2 - Skin Sens. 1
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3