SAB5701798

Anti-Phospho-PFKFB2-S483 antibody produced in rabbit

• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: liquid
• Speziesreaktivität: rat, mouse, human
• Konzentration: 1.44 mg/mL
• Methode(n): western blot: 1:500-1:2000
• UniProt-Hinterlegungsnummer: O60825
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer483)
• Angaben zum Gen: human ... PFKFB2(5208)

Beschreibung

Allgemeine Beschreibung

The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.

Immunogen

A synthetic phosphorylated peptide around S483 of human PFKFB2 (NP_006203.2).

Physikalische Form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable