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Merck

SAB4504122

Sigma-Aldrich

Anti-phospho-CaMK4 (pThr196/200) antibody produced in rabbit

affinity isolated antibody

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 51 kDa

Speziesreaktivität

human, mouse, rat

Konzentration

~1 mg/mL

Methode(n)

ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

phosphorylation (pThr196/pThr200)

Angaben zum Gen

human ... CAMK4(814)

Allgemeine Beschreibung

Calcium/calmodulin-dependent protein kinase IV (CAMK4) is a multifunctional serine/threonine protein kinase. It is present in cells of the nervous and immune systems. This gene is located on human chromosome 5q22.

Immunogen

The antiserum was produced against synthesized peptide derived from human CaMK4 around the phosphorylation site of Thr196/200.

Immunogen Range: 166-215

Biochem./physiol. Wirkung

Calcium/calmodulin-dependent kinase 4 (CAMK4) controls blood pressure.This protein plays a major role in the spermatogenesis by phosphorylating protamines.. It controls vascular tone. Absence of CaMK4 gene promotes hypertension.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: novel routes for an ancient traveller
Racioppi L and Means AR
Trends in Immunology, 29(12), 600-607 (2008)
CAMK4 gene variation is associated with hypertension in a Uygur population
Chen SZ, et al.
Genetics and molecular research : GMR, 15(1) (2016)
CaMK4 Gene Deletion Induces Hypertension
Santulli G
Journal of the American Heart Association (2012)
Akanksha Roy et al.
International journal of molecular sciences, 25(6) (2024-03-28)
Inherited retinal degenerative diseases (IRDs) are a group of rare diseases that lead to a progressive loss of photoreceptor cells and, ultimately, blindness. The overactivation of cGMP-dependent protein kinase G (PKG), one of the key effectors of cGMP-signaling, was previously
Genetic risk factors for the development of allergic disease identified by genome-wide association
Portelli MA, et al.
Clinical and Experimental Allergy, 45(1), 21-31 (2015)

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