SAB4300263

Anti-phospho-CFL1/CFL2 (pTyr⁸⁸) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-CFL antibody produced in rabbit, Anti-NEM7 antibody produced in rabbit, Anti-cofilin 1 (non-muscle) / cofilin 2 (muscle) antibody produced in rabbit
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: ~19 kDa
• Speziesreaktivität: human, mouse, rat
• Konzentration: 1 mg/mL
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• Isotyp: IgG
• Immunogene Sequenz: (A-T-YP-E-T)
• NCBI-Hinterlegungsnummer: NP_005498.1; NP_068733.1
• UniProt-Hinterlegungsnummer: P23528
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pTyr88)
• Angaben zum Gen: human ... CFL1(1072) , CFL2(1073)

Beschreibung

Immunogen

Peptide sequence around phosphorylation site of tyrosine 88 (A-T-Y(p)-E-T), according to the protein CFL1/CFL2.

Leistungsmerkmale und Vorteile

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Zielbeschreibung

Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable