SAB4300170

Anti-phospho-TH (pSer⁴⁰) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-TYH antibody produced in rabbit, Anti-tyrosine hydroxylase antibody produced in rabbit
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 55-60 kDa
• Speziesreaktivität: mouse, rat, human
• Konzentration: 1 mg/mL
• Methode(n): indirect immunofluorescence: 1:100-1:200
• Isotyp: IgG
• Immunogene Sequenz: (R-Q-SP-L-I)
• NCBI-Hinterlegungsnummer: NP_000351.2
• UniProt-Hinterlegungsnummer: P07101
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer40)
• Angaben zum Gen: human ... TH(7054)

Beschreibung

Immunogen

Peptide sequence around phosphorylation site of serine 40 (R-Q-S(p)-L-I), according to the protein TH.

Leistungsmerkmale und Vorteile

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Zielbeschreibung

The protein encoded by Tyrosine Hydroxylase is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable